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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ab79343b62ebadd341f3eb8bd83f029bb01aa1fc2afef84cb51308a61c2b98' 
  AND token = 'kzj1OjEO3TkSH08EsAYJWX86sk32YResLvxgMuKpui4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}