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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3d6d3b103f17c8a05c5b1a293087a07f1e09dede84de0827af5b20eada67b4' 
  AND token = '8lc1Xrap+vVbF0GAUhCoJO+7i1vWAI66/URBlRCyFU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}