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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99922b9d00b06c31e32ea965bdad5b5e3556fad9846dfa8e907cbd2e47d205f' 
  AND token = 'lY1MCFYGzO3olOsYZDJ8SWo49eHQqq4W6SKD6AuBuns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}