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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351d1c6fa5e2ac778361748fc95010ff6352a8ab0c6aa7c5cd9a564811a18c02' 
  AND token = 'A27BZFPIgIO/eBv4CMLJVBqp1V14YujsTe0s5VnwUsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}