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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c847e08ae96c36f34445f74096394cbac1dc10f8a02853dd9508ce718b33280f' 
  AND token = 'MlfC3+OR17UdhLv/l5Q1j9mxPQi/gM4bTqdHWcHE7+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}