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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded6209d67951c8d6d76889deb7af9333a9e728ab365f173a903260f54e4aa92' 
  AND token = 'QKifGuHi2kMZa4MFH30mgIlpe0hMj3HS1zaW+gG0m+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}