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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd2200eeb3586deb9c455c1471d056f52036af3045c68ac6d72329d292b017d' 
  AND token = 'w16om6lt1rtsB63wzXu5KkL9HNQ7tNbdYQd5FItoHpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}