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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd5a8314617ed398e3a32fc1e076d639efc7d5252f86981e481febe4691a6f4' 
  AND token = 'K3aR3qrbDn15j91nWvQuZsx/eO8C28HU0U9X8YQ2vRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}