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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9501cbfeff50b60506575eb5a058ac68df5edd97668fc5ff19aea20bf42310c8' 
  AND token = 'C2O2Kermq64bzr3eThXQcqZHmnfT5NLyzTXBgTnf6pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}