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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff26d9c5e176cce98224def0110df8d5433a8ee559a468988f970941587eaa1' 
  AND token = 'ZlvENCq0i7J+mQU4Y8gp7X3Lyft1Tci25+mnxAlwvLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}