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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d02fd808aa0a29396c7f59d8420d6d748874693b51467ad1db0a0c92a2860f8' 
  AND token = 'Fg3SkYHCYwhclp+8IGejFTLlDHko5f7xrH9DM6E3Kt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}