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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c71ebca59b6fb8b19bd07c5792a0576801226f6d1bed9b525bb904bbace6c4f' 
  AND token = 'T7iJ54MffFhvf5PT78TxPT9aJIA7WnWuPzVFN42nSaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}