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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457cdc06f2a8d1de7b65a1261199ab5ccf7638f981d9e69d4afe6eb4486a76b1' 
  AND token = 'gHi/lQ40Kl3G541wIh6noI3qQqCy3HxqI7WWtalC4YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}