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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb1c25e7d41abac56621a08545427d028b3f1bcebecf1099a4fa45541bd74c6' 
  AND token = '4wlXY7lBE8dHmwOI/UvEeAY7o8l/gWLAvebyqxgp4ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}