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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defe4945b4a68ecaea240706fc657cecae85cc7ffdb19c29f1cce040d8827d05' 
  AND token = 'JjnoXPS6Hy/pfnNpbaCAg2Wb0pdQ416/I/TBJ4E5l6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}