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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195b5dff5b5b16a8defb4ea1a833bc6f3bec73ef54127f2a087ad0b45df2c5d7' 
  AND token = 'e/WRvfnXiWdxsS2jWmdJGI+2sP+gDR1yccDVnbqfhXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}