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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95a3db06fd03f3c418d95a7a56287d77dfef22f07213621aeef560cddde7c29' 
  AND token = 'IyeBmqPw+XICHfbAjzTaMBl6GsZxdh9e4I4h1bIdDrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}