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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc46e655024ac2b28265c93ef3301f4c99da2227e41da5704cc41c9261cdef60' 
  AND token = 'VshQALLa0AGkmGF9UOo+99wmkpuyokiS7EYT9dzXwZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}