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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef33ba01e1eb653432866a6df63787f9238a0c745f38e425bd4263d843778a7d' 
  AND token = 'deOU8DYn/+NtkF0oNa5MLQil4lvOj9i6GkYUnl/v9VY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}