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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2578212ebb3e07457433b4afdbb996bf7ce9f366b787834da4ce4def41cbe98b' 
  AND token = 'wNbV0PBzHC2UireOS8VaQmM/PfpoBZal6iNFfRXqw7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}