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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb88e761da32ae4157093a9cb4ded6f707017edc56a5fde3afa07a470e735bf7' 
  AND token = 'cVOGs9qoSD5T6xeJ1Bm2eLfpa0+RyA6cNSDag0aTk6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}