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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dcd651009a101e15e4901417f61f564360f5aa338fe80a0d365eddfec90e3dd' 
  AND token = 'BaSmJJu+OV6/qPp1WZE200LPxKqQCZzURg4T7AjR9Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}