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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0730fbe75c07a4b418e700efcad9c2da7a99039b0f53491e50fabd493eb8090' 
  AND token = 'CFh/SZVyACuiv1H49TAOPa1nzXfqpFKPakWBUYvzJ5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}