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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51cceb9c241e3adf846b27984e019316eecfee8eb1143d25941c6a45477a0eb3' 
  AND token = 'QwY7eIjHJuft7LIhsqZlbSLrhynJu6hgMGZigD05Bp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}