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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1949dc35526d3e35bef51e685f47f477dce7d1f9b6b56d726c293dcc8e3b60c3' 
  AND token = 'sxIVVqZSnJchyWmx6c2SgxwaV1tWvBQn1NpguaDISAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}