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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412c6a07e575e3cdbc9e27d476d6f1dc91b7a7e23b7f3ea5424cf91136de0063' 
  AND token = 'toVSGckuVsPYU2sjaQIjJ+c1X1AZKxZEPDh4OwscWx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}