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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ebb3570877ac7e1c33595fae2c9b27c288f9e75a4c0eb5e5e1a12921ac49c6' 
  AND token = 'FaQCJ8DJ1x01HSdAtXW7w+06iACeEPdJk5Qq9trtr08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}