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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69f4e79fcdcd0708a09055a0d793dc3199dceca83c41e323be89f278863c6dd8' 
  AND token = 'l8msVlqZDmgK0JLzsp1XrBCuiYanMHZ3Vnq3eh8P7QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}