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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e8f337eea70cf2ece5f6d5498d3aa2bc0d5546a957f137fcf6b9b7cd550f42' 
  AND token = 'lz4GRaOD3VzYxtU8Y+piJW5UJf7AtQbyHPr4LZLuQPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}