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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce81374d968b98f37f854ae2e442c17c9adcbbf3b41503fb09d9c077f73b11c' 
  AND token = 'Ln2vFPQmtxWxNfGGsvWytouMzVnZ6WnvTtrCSRARRzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}