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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a089a7c0295919af0d0d3d57ac5a5be6d3feba5bb9f8845b663d929638a1947' 
  AND token = 'IIAehsfMs0Ng9z08Him/RH88NSIJrvoSZQ/1KF86b54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}