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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d215ff171e42cff07606aa822f2e617317bca8e6340b56287e5a26c6486a9c6' 
  AND token = 'qyAlJz0Lxpg+qVtaqcZsCYyB5+LH/KmryaCrz4ay61M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}