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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0fd6afc60ec2321f3ed86a22233523ae26749bbd8da2ffc467aac4208185ee' 
  AND token = '+9IkaAsrW8VLC2dYlp+B1JOrNHQh6adVEqmPnorobi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}