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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e34b73c352859053b6c9d68e35d6cf5ff83de9ad47e66121c33e8856e9c52b4' 
  AND token = 'mfRgTeRUfHaDGpjYujbA1hbs7bPE4KP6OtLfyYwUhPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}