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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49e77941bfe4e76c489cafcc0f272ba2874c3ced8eebca7616d9c0aa1a95f38' 
  AND token = 'noHFbCS15+1B+uToG53wXyPATq7lB00rab9Y9z+7ZHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}