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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7e15bfd540ec208e1e070d5cd2498a2f8b7f375d559fe0698efcd7939f210a' 
  AND token = 'J044TozQdWY/H11vl45g2QONFrgdRirEU6VMRbSUevE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}