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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490b700a6518dea8ce0d634efbd2968daaa5c2895e986e6b4d0c1e59e9586794' 
  AND token = 'e12SHR38uHDEkCzGmO2i3QKBJHuT/yTMJjisFukxMqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}