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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6409e12bf3e1a86fc71f3d9fc835e03f6984505d3da41222e4322d9f57b9ea' 
  AND token = 'c1wDLAMRv3pwa0TmJDat+oUbOFNv+Q6Tx+YRxh0vao4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}