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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fab5a393fa4bf41c8d5af3b40a09e86148800112289c598ca8453b668a5564' 
  AND token = 'yVb+ZA4koig59h80vL6oV72YlvMHGEEqE7PR4JvGsMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}