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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc3f921186b103608bcb8f71c2b5797446be3b8d78218c4e173f81b17b12e8a1' 
  AND token = 'Q27dOxrgRWLITAYv3OVus5PcwJAQCe0Lu5QlPze17nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}