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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf6e2526ff2946eb91e1648a54b16aac9f09e7a91813cfbadcee278b5585c06' 
  AND token = '8HE+ZPmZbNrB2lMB3TuNTcp/c4yTu1zDlr6V5b2bq4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}