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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd62efbaa0d487009d0b78277549e41633bfb3c7c4d842412e3b30b80ce043885' 
  AND token = '+/hO1F4XIGG2XMywQnCPBMDqOAgRX9q2iCBpEW0Mf7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}