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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c6bf1b8cd3a890b7742dd043005c2fd4f547f06d403a70e41466796b6c07d3' 
  AND token = '34/uqld7CgLAW2+8+pXfvg1+Uu3TAeWZUcotAj5MAVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}