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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654e8708241d8e876e71faf41c017f0c77c7132f882d2b18da6b323db0d88818' 
  AND token = 'Flbz3x23dvEp+r4iROI4Rb7Be4faMXH1IVUF1QAzUbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}