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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e814e3d6f9849e5db1c722e89e8f41f2bb8ac6a12a528a0dd640e658df84855' 
  AND token = 'FP+kPVdXoogaE5mrC+ciVKuPSJbR63ZOGhKiSLCFpyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}