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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e22a782d2f3595d8b19ce8fa873402018ad0cfc80c1b326839d361f0f454848' 
  AND token = 'sa6a69whW3Q6wcnKicObLhL6kx+C+/zPXs/Jdg7CFUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}