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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd38e0d90d0499480f5b7502d3af5ea202f89dd7b510ad9a1eb39600e1f36a212' 
  AND token = 'SVMLRAeXtUsGzj5PvmliCL5K4M6BwUqJJ4JKeisnJow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}