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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f022133b6a87d957ec24f95ffb6146eeef81ac15345f0f232ac58710ea72fa0a' 
  AND token = 'zaH3mDXcBL5FK15EC1qos71df2fVfF+yRV53aqQtxeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}