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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45c52707d51a7c8c1ddb748788e5c51f551b8aa70aa24862c550db049c14c84' 
  AND token = 'JEivAqjY8q2i4su4iDRC1CiKNOxSlLt2nrCyk+DVSNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}