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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a41b5fa9794f48c3da5f982b2aa8e6bcde1bc921e87b752d9ada774ecef1272' 
  AND token = 'cHQ3wR0a2V6Zp1L+PcyZgvErvQ8VkPYdwagDJoZcFnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}